**Job Description**
This collaborative research project, situated within the VIB-Center for Inflammation Research and led by the Guilliams and Saelens teams, aims to decipher the molecular mechanisms orchestrating liver regeneration. Supported by an ERC Advanced Grant (2025 – 2030), the project will employ in vivo CRISPR screens to investigate how individual liver modules maintain their integrity during growth, offering a paradigm shift from a hepatocyte-centric view. The ultimate goal is to manipulate these molecular circuits to enhance the liver’s regenerative capacity, addressing significant challenges in human regenerative medicine where adult liver regeneration is limited. The successful candidate will integrate into an interdisciplinary team, utilizing novel probabilistic deep-learning models to analyze in vivo perturbational omics data and extract mechanistic and statistical insights.
**Skills & Abilities**
• Excellent communication skills
• Fluency in English
• Collaborative mindset
• Enthusiasm to work in an international and interdisciplinary environment
• Experience with highly multiplexed flow cytometry (Bonus)
• Experience with confocal microscopy (Bonus)
• Experience in single-cell or spatial omics (Bonus)
**Qualifications**
Required Degree(s) in:
• Bio-engineering
• Medicine
• Molecular biology
• Immunology
• Related fields
Other:
• FELASA certification
**Experience**
Experience Required:
• In regeneration, immunology, or hepatology (strong interest in all required).
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