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August 28, 2025

**Job Description**
This position involves joining a collaborative research program focused on the functional specialization of liver macrophages using in vivo CRISPR screens. The project aims to unravel causal circuits driving the development and functional specialization of liver-resident Kupffer cells and to study the effects of macrophage perturbations on neighboring stromal and endothelial cells using Spatial CRISPR screens. The successful candidate will be part of an interdisciplinary team applying novel probabilistic deep-learning models to analyze in vivo perturbational omics data.

**Skills & Abilities**
� Excellent communication skills and fluency in English.
� A collaborative mindset and enthusiasm to work in an international and interdisciplinary environment.
� Experience with highly multiplexed flow cytometry and confocal microscopy.
� Experience in single-cell or spatial multi-omics.

**Qualifications**
Required Degree(s) in:
� Bio-engineering
� Medicine
� Molecular Biology
� Immunology
� Related fields

**Experience**
Experience Required:
� Experience in either immunology or hepatology. Strong interest in both.
Other:
� FELASA certification

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Experience
Experience Required: � Experience in either immunology or hepatology. Strong interest in both. Other: � FELASA certification
Work Level
Ph.D, Postdoc
Employment Type
Scholarship, See Details
Salary
Benefits: Competitive salary and full benefits.
Details
See Details
School / Department / Center / Lab
� VIB-Center for Inflammation Research � Guilliams and Saelens team
Supervisor(s)
Prof. Martin Guilliams Prof. Wouter Saelens
Supervisor Email
martin.guilliams@irc.vib-ugent.be wouter.saelens@irc.vib-ugent.be
Vlaams Instituut voor Biotechnologie (VIB)
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