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August 28, 2025

**Job Description**
This role involves joining a collaborative research program within the VIB-Center for Inflammation Research, specifically with the Guilliams and Saelens teams. The project focuses on applying in vivo CRISPR screens to study the functional specialization of macrophages during liver metastasis, supported by a Foundation against Cancer grant (2025-2030). The research will unravel causal circuits driving the development and functional specialization of immunosuppressive tumor-associated macrophages (TAMs), focusing on their crosstalk with cancer-associated fibroblasts (CAFs) and the effects of macrophage perturbations on stromal cells. The work utilizes state-of-the-art in vivo perturbational technologies and advanced computational modeling within an interdisciplinary team.

**Skills & Abilities**
� Excellent communication skills and fluency in English.
� Collaborative mindset and enthusiasm to work in an international and interdisciplinary environment.
� Experience with highly multiplexed flow cytometry and confocal microscopy.
� Experience in single-cell or spatial omics.

**Qualifications**
Required Degree(s) in:
� Bio-engineering
� Medicine
� Molecular Biology
� Immunology
� Related fields
Other:
� FELASA certification

**Experience**
Other:
� Experience in either cancer, immunology, stromal cells, or hepatology. Strong interest in all.

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Experience
Other: � Experience in either cancer, immunology, stromal cells, or hepatology. Strong interest in all.
Work Level
Ph.D, Postdoc
Employment Type
Scholarship, See Details
Salary
Annual Salary: Competitive salary Benefits: Full benefits
Details
See Details Location Requirement: On-site
School / Department / Center / Lab
� VIB-Center for Inflammation Research � Guilliams team � Saelens team
Supervisor(s)
Prof. Martin Guilliams Prof. Wouter Saelens
Supervisor Email
martin.guilliams@irc.vib-ugent.be wouter.saelens@irc.vib-ugent.be
VIB / Ghent University
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