PhD Candidate / Postdoctoral Fellow

**Job Description**
A motivated PhD candidate or Postdoctoral fellow is sought to join a collaborative research program within the VIB-Center for Inflammation Research, specifically within the Guilliams and Saelens teams. The project, supported by an ERC Advanced Grant, focuses on applying in vivo CRISPR screens and single-cell/spatial multi-omics technologies to study the functional specialization of liver macrophages, particularly liver-resident Kupffer cells. The role involves unraveling causal circuits driving their development and specialization, and developing Spatial CRISPR screens to understand macrophage perturbations’ effects on neighboring stromal and endothelial cells, ultimately decoding their relationship to hepatic stromal and endothelial cells at unprecedented speed and resolution. The successful candidate will be embedded in an interdisciplinary team utilizing novel probabilistic deep-learning models to extract biological and statistical knowledge from in vivo perturbational omics data.

**Skills & Abilities**
� Excellent communication skills and fluency in English.
� A collaborative mindset and enthusiasm to work in an international and interdisciplinary environment.
� Experience with highly multiplexed flow cytometry and confocal microscopy.
� Experience in single-cell or spatial multi-omics.

**Qualifications**
Required Degree(s) in:
� Bio-engineering
� Medicine
� Molecular biology
� Immunology
� Related fields
Other:
� FELASA certification

**Experience**
Other:
� Experience in either immunology or hepatology.

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