Postdoctoral Researcher

**Job Description**
This postdoctoral position focuses on investigating SET as a dependency and therapeutic target in paediatric Acute Myeloid Leukaemia (AML), a leading cause of childhood leukemic mortality with an unmet need for new targeted therapies. The role involves employing an integrated molecular approach, including RNA-seq, ChiP-seq, mouse modelling, and gene silencing technology, to improve overall survival in children with AML. The research builds on the team’s recent discovery linking high SET expression to worse survival and its role in abrogating AML clonogenic potential.

**Skills & Abilities**
• Experience of working in cancer signalling or related fields
• Expertise in working with mice
• Flow cytometry
• Mammalian cell culture
• Molecular biology techniques
• Experience with ChiP and Cut&Run (advantageous)
• Experience in leukaemia/haematopoietic stem cells (advantageous)
• Strong track-record of high-quality peer reviewed research
• Excellent communication skills with a very high level of written and spoken English
• Self-motivated
• Collaborative
• Independent thinker
• Excellent organisational skills
• Genuine passion for research
• Contributing to a supportive and inclusive research environment

**Qualifications**
Required Degree(s) in:
• Biochemistry
• Molecular biology
• Cell biology
• Related areas
Other:
• Completed or near to completing a PhD

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